Revolutionizing Biologics: From Injection to Ingestion

Our ML/AI enabled platform transforms life-changing therapies into accessible oral formulations.

10x
Patient Compliance
3+
Therapeutic Areas
ML
Driven Platform
What We Do

Transforming Healthcare Delivery

Our oral biologic platform creates substantial value across the entire healthcare ecosystemโ€”from patients to payers to providers.

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Benefits for the Patient

The patient experiences the most direct "quality of life" improvements.

Elimination of Needle Anxiety

Approximately 10% of the population suffers from needle phobia, which can lead to treatment avoidance. Oral delivery removes this critical barrier to therapy.

Greater Convenience & Autonomy

Patients can take their medication at home, at work, or while traveling, rather than scheduling appointments at infusion centers or clinics.

Reduced Pain and Site Reactions

Oral delivery avoids the bruising, swelling, and localized pain common with subcutaneous injections and IV lines.

Lower Infection Risk

Bypasses the risk of cannula-related infections or secondary bacterial/fungal infections associated with repeated skin punctures.

Improved Adherence

Research suggests patients are more likely to stick to a long-term treatment plan when it involves a simple pill rather than a complex or painful injection schedule.

More Physiological Delivery

For certain drugs like insulin, oral delivery can better mimic the body's natural pathways (portal circulation to the liver) rather than systemic absorption via fat tissue.

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Benefits for the Payers (Insurance/Government)

Payers see significant value in reducing the "hidden" costs of healthcare.

Lower Unit Costs

Oral formulations often do not require the same sterile manufacturing environments as parenterals, potentially lowering the base price of the drug.

Elimination of Administration Fees

Payers no longer have to reimburse for nursing time, facility fees for infusion centers, or specialized equipment (needles, syringes, IV kits).

Reduction in Complication Costs

Lowering the rate of injection-site infections or infusion-related adverse reactions reduces the cost of secondary care.

Increased Competitive Markets

The introduction of oral versions of existing biologics can drive competition and lower prices across the therapeutic class.

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Benefits for the Healthcare System

The broader system benefits from improved efficiency and resource allocation.

Reduced Burden on Staff

Frees up nurses and clinicians from the time-consuming task of administering injections and monitoring patients during long infusions.

Optimized Facility Use

Reduces the need for dedicated infusion chairs and clinic space, allowing hospitals to focus resources on patients with more acute needs.

Waste Reduction

Eliminates the medical waste associated with disposables like needles, biohazard sharps containers, and plastic IV tubing.

Earlier Disease Intervention

Because oral meds are easier to prescribe and take, doctors may be able to start effective biologic therapy earlier in the disease progression, potentially preventing long-term disability or expensive hospitalizations.

Our Platform

ML/AI-Driven Formulation Engine

Leveraging machine learning and artificial intelligence to revolutionize how biologics are formulated and delivered.

Computational Drug Formulation Design

Traditional formulation development relies on trial-and-error approaches that take years and millions of dollars. Our ML platform analyzes thousands of molecular interactions simultaneously, predicting optimal formulation parameters in weeks, not years.

By integrating physicochemical properties, biological pathways, and delivery kinetics, our AI identifies the precise combination of excipients, protective coatings, and release mechanisms needed for each unique biologic.

1

Predictive Modeling

AI algorithms predict formulation success rates before synthesis

2

Rapid Optimization

Machine learning accelerates formulation cycles from years to months

3

Data-Driven Insights

Continuous learning from experimental results improves platform accuracy

01
Drug Characterization

AI analyzes molecular structure, stability, and absorption properties

02
Formulation Prediction

ML models generate optimal excipient combinations and coating strategies

03
In Silico Testing

Virtual simulations predict gastric protection and intestinal release

04
Validation & Iteration

Experimental data feeds back into models for continuous improvement

Development Pipeline

Therapeutic Programs

Our diverse pipeline targets multiple high-impact therapeutic areas with significant unmet medical needs.

Discovery
Preclinical
Phase 1
Phase 2
Phase 3

Immunology

Discovery
Preclinical
Phase 1
Phase 2
Phase 3

Rheumatoid Arthritis

Oral anti-TNF monoclonal antibody formulation

Discovery
Preclinical
Phase 1
Phase 2
Phase 3

Inflammatory Bowel Disease

Oral integrin antagonist for Crohn's and UC

Discovery
Preclinical
Phase 1
Phase 2
Phase 3

Cardiology

Oral PCSK9 inhibitor for cardiovascular disease prevention

Discovery
Preclinical
Phase 1
Phase 2
Phase 3

Oncology

Oral checkpoint inhibitor immunotherapy platform

Discovery
Preclinical
Phase 1
Phase 2
Phase 3
Partnerships & Collaboration

Building the Future Together

We're actively seeking strategic partnerships with pharmaceutical companies, research institutions, and investors who share our vision of transforming biologic drug delivery.

Interested in partnering with Oralyx Bio? We'd love to explore collaboration opportunities in drug development, licensing, or investment.

Contact Us
Leadership

Our Team

World-class expertise in drug formulation, ML/AI, and drug-device combination products.

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Dr. Sarah Chen

CEO & Co-Founder

Former VP of Formulation Sciences at a leading biotech company with 15+ years developing novel drug delivery systems. Led development of 12 approved products and holds multiple patents in oral biologic delivery. PhD in Pharmaceutical Sciences from MIT.

Latest Updates

News & Press

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Jan 15, 2026

Oralyx Bio Announces $45M Series A Funding

Leading venture firms invest in revolutionary oral biologic delivery platform, accelerating pipeline development and bringing the company's ML-enabled formulation technology closer to clinical trials.

Get In Touch

Contact Us

Interested in partnerships, investment opportunities, or learning more? We'd love to hear from you.

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Headquarters

Malvern, PA 19355
United States

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Email

info@oralyxbio.com

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Partnerships

partnerships@oralyxbio.com

๐Ÿ“ Malvern, PA Location Map